ampk activator aicar Search Results


ampk activator aicar  (ApexBio)
90
ApexBio ampk activator aicar
Ampk Activator Aicar, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/ampk+activator+aicar/pm40247356-83-12-15
Average 90 stars, based on 1 article reviews
ampk activator aicar - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
aicar (an ampk activator, cat no. b1211)  (ApexBio)
90
ApexBio aicar (an ampk activator, cat no. b1211)
PA-induced pancreatic β-cell dysfunction is related to NAD <t>+</t> <t>/AMPK/SIRT1/HIF-1α</t> signaling pathway regulation. ( A ) Cell viability of INS-1 cells treated by different <t>AICAR</t> concentrations. ( B ) The secretion level of INS-1 cells treated with 0.5 mM PA and/or 0.5 mM AICAR. Measurement 3.3 mM represents 3.3 mM glucose concentration simulating normal fasting glucose levels, while 16.7 mM represents 16.7 mM glucose concentration reflecting postprandial hyperglycemia. Insulin levels were measured after stimulation with 3.3 mM glucose and 16.7 mM glucose after 1 h of incubation. ( C ) The NAD + /NADH ratio of INS-1 cells treated by 0.5 mM PA and/or 0.5 mM AICAR. ( D ) Representative Western blotting of HIF-1α, SIRT1, pAMPK, AMPK, Glut2, and GAPDH in INS-1 cells. ( F ) p-AMPK/AMPK ratio. ( E , G , H ) Quantitative density analysis of Glut2, SIRT1, and HIF-1α normalized to GAPDH. Data are expressed as mean ± SD ( n = 3). Each circle represents a replicate experiment. * p < 0.05, ** p < 0.01 vs. the control group; # p < 0.05 vs. the PA group.
Aicar (An Ampk Activator, Cat No. B1211), supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/AICAR++an+AMPK+activator++Cat+No++B1211/pmc11476918-133-0-19
Average 90 stars, based on 1 article reviews
aicar (an ampk activator, cat no. b1211) - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
ampk analogs/activators aicar  (PeriCor LLC)
90
PeriCor LLC ampk analogs/activators aicar
Small molecule compounds in development or clinical use for treatment of uveitis
Ampk Analogs/Activators Aicar, supplied by PeriCor LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/ampk+analogs+activators+aicar/pmc08172489-48-0-22
Average 90 stars, based on 1 article reviews
ampk analogs/activators aicar - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
cell-permeant ampk activator 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (aicar)  (Biomol GmbH)
90
Biomol GmbH cell-permeant ampk activator 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (aicar)
Small molecule compounds in development or clinical use for treatment of uveitis
Cell Permeant Ampk Activator 5 Aminoimidazole 4 Carboxamide 1 β D Ribofuranoside (Aicar), supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/cell+permeant+ampk+activator+5+aminoimidazole+4+carboxamide+1+%CE%B2+d+ribofuranoside++aicar+/pmc03798744-53-1-18
Average 90 stars, based on 1 article reviews
cell-permeant ampk activator 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (aicar) - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
ampk activator aicar  (FUJIFILM)
90
FUJIFILM ampk activator aicar
( A ) PPARγ activator RSZ or <t>AMPK</t> activator <t>AICAR</t> markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).
Ampk Activator Aicar, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/ampk+activator+aicar/pmc06435468-55-17-22
Average 90 stars, based on 1 article reviews
ampk activator aicar - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
ampk activator aicar gc10518  (GlpBio Technology Inc)
90
GlpBio Technology Inc ampk activator aicar gc10518
( A ) PPARγ activator RSZ or <t>AMPK</t> activator <t>AICAR</t> markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).
Ampk Activator Aicar Gc10518, supplied by GlpBio Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/ampk+activator+aicar+gc10518/pm37621136-47-0-9
Average 90 stars, based on 1 article reviews
ampk activator aicar gc10518 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
aicar, and ampk activator  (Tamiya Inc)
90
Tamiya Inc aicar, and ampk activator
( A ) PPARγ activator RSZ or <t>AMPK</t> activator <t>AICAR</t> markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).
Aicar, And Ampk Activator, supplied by Tamiya Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/aicar++and+ampk+activator/pm16762646-192-26-2
Average 90 stars, based on 1 article reviews
aicar, and ampk activator - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
1 mm amp-activated protein kinase (ampk) activator (aicar)  (FUJIFILM)
90
FUJIFILM 1 mm amp-activated protein kinase (ampk) activator (aicar)
( A ) PPARγ activator RSZ or <t>AMPK</t> activator <t>AICAR</t> markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).
1 Mm Amp Activated Protein Kinase (Ampk) Activator (Aicar), supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ampk+activator+aicar/1+mm+amp+activated+protein+kinase++ampk++activator++aicar+/pm26101135-107-16-22
Average 90 stars, based on 1 article reviews
1 mm amp-activated protein kinase (ampk) activator (aicar) - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


PA-induced pancreatic β-cell dysfunction is related to NAD + /AMPK/SIRT1/HIF-1α signaling pathway regulation. ( A ) Cell viability of INS-1 cells treated by different AICAR concentrations. ( B ) The secretion level of INS-1 cells treated with 0.5 mM PA and/or 0.5 mM AICAR. Measurement 3.3 mM represents 3.3 mM glucose concentration simulating normal fasting glucose levels, while 16.7 mM represents 16.7 mM glucose concentration reflecting postprandial hyperglycemia. Insulin levels were measured after stimulation with 3.3 mM glucose and 16.7 mM glucose after 1 h of incubation. ( C ) The NAD + /NADH ratio of INS-1 cells treated by 0.5 mM PA and/or 0.5 mM AICAR. ( D ) Representative Western blotting of HIF-1α, SIRT1, pAMPK, AMPK, Glut2, and GAPDH in INS-1 cells. ( F ) p-AMPK/AMPK ratio. ( E , G , H ) Quantitative density analysis of Glut2, SIRT1, and HIF-1α normalized to GAPDH. Data are expressed as mean ± SD ( n = 3). Each circle represents a replicate experiment. * p < 0.05, ** p < 0.01 vs. the control group; # p < 0.05 vs. the PA group.

Journal: International Journal of Molecular Sciences

Article Title: Nicotinamide Mononucleotide (NMN) Ameliorates Free Fatty Acid-Induced Pancreatic β-Cell Dysfunction via the NAD + /AMPK/SIRT1/HIF-1α Pathway

doi: 10.3390/ijms251910534

Figure Lengend Snippet: PA-induced pancreatic β-cell dysfunction is related to NAD + /AMPK/SIRT1/HIF-1α signaling pathway regulation. ( A ) Cell viability of INS-1 cells treated by different AICAR concentrations. ( B ) The secretion level of INS-1 cells treated with 0.5 mM PA and/or 0.5 mM AICAR. Measurement 3.3 mM represents 3.3 mM glucose concentration simulating normal fasting glucose levels, while 16.7 mM represents 16.7 mM glucose concentration reflecting postprandial hyperglycemia. Insulin levels were measured after stimulation with 3.3 mM glucose and 16.7 mM glucose after 1 h of incubation. ( C ) The NAD + /NADH ratio of INS-1 cells treated by 0.5 mM PA and/or 0.5 mM AICAR. ( D ) Representative Western blotting of HIF-1α, SIRT1, pAMPK, AMPK, Glut2, and GAPDH in INS-1 cells. ( F ) p-AMPK/AMPK ratio. ( E , G , H ) Quantitative density analysis of Glut2, SIRT1, and HIF-1α normalized to GAPDH. Data are expressed as mean ± SD ( n = 3). Each circle represents a replicate experiment. * p < 0.05, ** p < 0.01 vs. the control group; # p < 0.05 vs. the PA group.

Article Snippet: AICAR (an AMPK activator, Cat No. B1211) and Compound C (CC, an AMPK, Cat No. B3252) were obtained from APExBIO.

Techniques: Concentration Assay, Incubation, Western Blot, Control

Small molecule compounds in development or clinical use for treatment of uveitis

Journal: International Ophthalmology

Article Title: New pharmacotherapy options for noninfectious posterior uveitis

doi: 10.1007/s10792-021-01763-8

Figure Lengend Snippet: Small molecule compounds in development or clinical use for treatment of uveitis

Article Snippet: AMPK analogs/activators AICAR , AMPK/ reduces NF-κB signaling, JAK-STAT signaling, leukocyte infiltration and cytokine synthesis , Preclinical [ ] , Intraperitoneal , PeriCor Therapeutics, Schering-Plough.

Techniques:

( A ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).

Journal: Bioscience Reports

Article Title: Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer’s disease: possible mechanisms of IDE in T2D and AD

doi: 10.1042/BSR20170862

Figure Lengend Snippet: ( A ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the IDE activity. ( B ) PPARγ activator RSZ or AMPK activator AICAR markedly increased the mRNA expression level of IDE. ( C ) The protein expression level of IDE was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. ( D ) The protein expression level of PPARγ was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( E ) The protein expression level of AMPK was also significantly increased after treatment of PPARγ activator RSZ or AMPK activator AICAR. PPARγ. ( F ) After treatment with PPARγ activator RSZ or AMPK activator AICAR, the levels of soluble Aβ40 and Aβ42 were significantly decreased in mice with AD and T2D ( n = 10 in each group, means ± SEM, # P <0.05 compared with the APP/PS1 group, and @ P <0.05 compared with the APP/PS1 + STZ group).

Article Snippet: Cruz Biotechnology, Santa Cruz, CA) (APP/PS1 + STZ + RSZ group), or received an intraperitoneal injection of AMPK activator AICAR (500 mg/kg; Wako PureChemicals Industries Ltd, Osaka, Japan) (APP/PS1 + STZ + AICAR group).

Techniques: Activity Assay, Expressing